Is our healthcare system ready for menopause? Nurse practitioner Lexi Yoo says “definitely not,” and she’s building what comes next.
Too many women in perimenopause and menopause walk out of their doctor’s office with a prescription for Ambien or Lexapro and no real answers. Lexi Yoo hears that story every week. She’s a nurse practitioner with a foundation in functional and longevity medicine. She’s also going through this stage of life herself, and she believes her generation will change what menopause looks like for decades to come.
In this episode of the Unsee Podcast, host Leonard Pastrana, PharmD, talks with Lexi about her path from pediatric trauma care to functional medicine. They cover how she grew one practice into two locations with about 3,000 patients, how she uses peptides alongside hormone therapy, and why medical education takes decades to catch up.
Lexi also shares what nurse practitioners need to know about scope of practice and working with physicians, how patient education improves outcomes, and the risks of getting health advice from social media.
In this episode:-Why so many women feel unheard in perimenopause and menopause care-How hormone optimization and peptides fit into a women’s health practice-Leaving traditional medicine and scaling a functional medicine practice-Scope of practice, mentorship, and collaboration between NPs and physicians-Social media, AI, and the double-edged sword of online health information
Chapters00:00 Introduction01:48 Lexi Yoo's Path: From Pediatric Trauma NP to Functional Medicine04:29 Bariatrics, Weight Loss & Discovering Functional Medicine07:14 Leaving Traditional Medicine to Start Her Own Practice08:04 Scaling to 2 Locations & 3,000 Patients09:33 How She Started Using Peptides11:59 Hormone Therapy vs. Peptides: What Peptides Add13:05 Living What You Teach in Longevity Medicine15:16 Why Sales Isn't a Dirty Word in Medicine17:58 What Drives Her Now20:03 Why Teaching Makes You a Better Clinician22:09 Patient Education That Improves Outcomes25:26 Why She Focuses on Perimenopause & Menopause27:21 How Each Generation Approaches Menopause28:20 Why Medical Schools Are Decades Behind29:11 Nurse Practitioner Scope of Practice & Working With Physicians34:16 Mentorship & Investing in Your Education37:53 Building a Clinic Culture Where No Question Is Stupid40:33 Bringing Your Team to Medical Conferences46:29 Her Upcoming Book on Perimenopause47:50 Social Media, AI & Online Health Misinformation49:23 Final Thoughts
Episode LinksFollow Lexi: https://www.instagram.com/lexiyoonp Learn more about nuBioAge: https://nubioage.com/register/?utm_source=podcast&utm_medium=organicLearn more about the CALM conference : https://calm.nubioage.com/?utm_source=podcast&utm_medium=organicFollow Leonard on Instagram:https://www.instagram.com/leonardpastrana

How many doctors are selling research peptides to their patients without realizing it?
Pharmacist and compounding pharmacy owner Dr. Franck Kacou joins Leonard Pastrana to break down one of the most misunderstood issues in peptide therapy: the difference between peptides compounded by a licensed pharmacy and products labeled "for research use only."
Franck has spent over a decade running a compounding pharmacy now licensed in multiple states, and he's watched peptides go from a physician-led niche to what he calls "the social media economy." In this conversation, he and Leonard get into:
• Research vs. compounded peptides, and why the raw ingredient makes all the difference• Why research peptides are so cheap, and what that price is really telling you• How physicians unknowingly buy and sell research peptides to their patients• Why a certificate of analysis (C of A) doesn't tell you as much as you think• How to verify you're actually buying from a licensed 503A or 503B pharmacy• The GLP-1 shortage and how it changed the way physicians buy medications• The FDA Pharmacy Compounding Advisory Committee peptide vote, and what it could mean for compounded peptides• The growing push to bypass physicians with direct-to-consumer models
Franck also shares how burning out in traditional retail pharmacy led him to functional and longevity medicine, and the moment he couldn't unsee.
This episode is for educational purposes only and is not medical advice. An FDA advisory committee recommendation is not FDA approval. Talk to your licensed healthcare provider before starting any peptide or medication.
Chapters00:00 Introduction02:39 Inside a Multi-State Compounding Pharmacy03:25 How BPC-157 Started the Peptide Boom05:35 Research Peptides vs. Compounded Peptides13:58 Why Research Peptides Are So Cheap16:39 How to Verify a Legit 503A or 503B Pharmacy20:00 503A vs. 503B, GLP-1 Shortage & State Crackdowns24:57 Retatrutide & the GLP-1 Black Market28:02 Can You Trust a Certificate of Analysis (C of A)?34:21 The Future of Peptide Therapy & Liability40:48 FDA Peptide Vote Explained (PCAC)44:48 Why Doctors Are Being Bypassed52:37 Why Every Doctor Needs to Understand Peptides55:15 From Pharmacy Burnout to Longevity Medicine
Connect with Franck: https://www.linkedin.com/in/franck-kacou-pharm-d-mba/Learn more about nuBioAge: https://nubioage.com/register/?utm_source=podcast&utm_medium=organicLearn more about the CALM conference : https://calm.nubioage.com/?utm_source=podcast&utm_medium=organicFollow Leonard on Instagram:https://www.instagram.com/leonardpastrana

Two physicians. Same training, same certifications, same protocols. One has a waitlist. The other is struggling to fill the schedule. The difference usually isn't the medicine. It's the brand.
Leonard Pastrana, PharmD, sits down with brand strategist Kelly Binnings, former Chief Brand Officer at nuBioAge, now leading ecosystem and strategic partnerships, to break down what brand actually means for physicians moving into cash-based, relationship-driven care.
It's not the logo or the website. It's how your team answers the phone, how patients are treated when leadership isn't around, and whether people experience what you say you stand for.
In this episode:→ The real difference between brand and marketing→ Why physicians are now small business owners who have to earn trust→ What it means to "operationalize" a brand inside your practice→ Why consistency feels boring and why it works→ Word of mouth as the most powerful growth channel in healthcare→ How you measure brand when there's no clean KPI (value, consistency, and authenticity signals)→ Neuroaesthetics: how the brain and body respond to brand experiences→ Phenomenology and why subjective experience still matters in data-driven medicine→ How the room design at CALM changed how a skeptical physician received the content→ Masterminds, community, and finding your tribe→ Kelly's book, Breakout Creative
You can't fake a brand, at least not for long. Get clear on your North Star, surround yourself with people who share it, and the brand takes care of itself.—Follow Kelly:  https://www.instagram.com/kbinnings/ Learn more about nuBioAge: https://nubioage.com/register/?utm_source=podcast&utm_medium=organicLearn more about the CALM conference : https://calm.nubioage.com/?utm_source=podcast&utm_medium=organicFollow Leonard on Instagram:https://www.instagram.com/leonardpastrana 
This content is for educational purposes only and is not medical advice.
00:00 Introduction00:44 Opening02:27 From print designer to brand strategist03:12 Brand vs. marketing04:15 Building nuBioAge's brand from the ground up05:56 What branding actually means07:52 Why physicians need a brand in cash-based medicine10:39 Operationalizing your brand13:51 Consistency is the whole game16:01 Same training, different results: the patient experience18:53 Word of mouth and building CALM21:17 Partnerships built on a shared mission24:03 Why brand is hard to put a dollar amount on25:45 Live events in the age of AI28:03 Neuroaesthetics and measuring brand through signals30:42 Phenomenology: subjective vs. objective data in medicine33:32 Why a skeptic felt different walking into CALM34:51 The Ritz-Carlton standard for medical events35:49 How great events quietly build community37:52 Bringing marketing-conference energy to medical education39:06 Becoming a category of one39:51 Why masterminds work42:49 Kelly's book: Breakout Creative44:01 Leonard's biggest brand lesson: you can't fake it46:44 Wrap-up

Some moments change how you see medicine forever. Once you see them, you can't unsee them.
For Dr. Haleem Mohammed, known as Dr. Hal, one of those moments happened at home. He was a chief medical officer managing thousands of employees, and he had reached 255 pounds. His wife, also a physician, asked him a question he couldn't ignore: would he be around after they had a baby?
He resigned, rebuilt how he lived, and rebuilt how he practiced. Today he's a board-certified internist, Chief Medical Officer of Gameday Men's Health, runs his own concierge practice, and serves on the FDA's Pharmacy Compounding Advisory Committee.
Leonard and Dr. Hal go from Wall Street to the FDA hearing room. They talk about how insurance shapes what doctors can and can't do, and why he tells some men they don't need testosterone. They cover what a network of hundreds of clinics reveals that a single practice can't, and what it was like to push back during a committee meeting on the future of compounded peptides.
In this episode:-His path from stockbroker to chief medical officer-The 255-pound wake-up call that changed his life and his medicine-How insurance shapes what doctors are allowed to do-The difference between a low testosterone number and testosterone deficiency-His advice for doctors who want out of the insurance model-What the FDA advisory committee actually does, and what it doesn't-What drives him now
This podcast is for educational purposes only and is not medical advice. Talk with your healthcare provider before making changes to your care.
Follow Dr. Hal on Instagram: https://www.instagram.com/healthwithdrhal Learn More About Gameday Men's Health: https://gamedaymenshealth.com/Learn more about nuBioAge: https://nubioage.com/register/?utm_source=podcast&utm_medium=organicLearn more about the CALM conference : https://calm.nubioage.com/?utm_source=podcast&utm_medium=organicFollow Leonard on Instagram:https://www.instagram.com/leonardpastrana
Chapters 00:00 Introduction 00:58 From Wall Street to Medicine 10:07 Building Gameday Men's Health 12:35 Insurance Medicine vs. Whole-Patient Care 15:43 Who Your Insurance Company Really Works For 16:34 What Hundreds of Clinics Reveal 18:39 "You Don't Need Testosterone" 19:52 The Problem With Some HRT Clinics and Med Spas 22:36 "My Goal Is to Not Have Any Patients" 24:11 Advice for Doctors Stuck in the Insurance Model 25:37 Collaboration Over Competition 27:41 Separating Signal From Noise 31:01 Why He Still Sees Patients 31:28 Inside the FDA Compounding Committee 33:39 Old Guard vs. New Guard 35:04 "I Think We Did the Right Thing That Day" 36:33 What Drives Him 39:58 Where to Find Dr. Hal

Some moments change how you see medicine forever. Once you see them, you can’t unsee them.
Dr. Kris Wusterhausen was doing everything he’d been taught. He was running a county clinic, he was burned out, his weight had climbed to 199 pounds, and his A1C had reached 6.2. Fixing his own health changed how he practiced medicine. In his words, it took him from a widely accepted family doctor to “the kooky doctor in town.” Years later, some of the doctors who called him kooky became his patients.
Today he’s a board-certified family physician and founder of The Resurge Clinic in Weatherford, Texas. He trains physicians in hormone and peptide therapy and serves on the FDA’s Pharmacy Compounding Advisory Committee.
Leonard and Dr. Kris go inside the committee meeting where BPC-157 and other peptides were reviewed. They cover what the committee was actually asked to decide, and why real-world clinical data deserves a seat at the table. Dr. Kris also shares the financial reality of leaving traditional medicine, his keep-it-simple approach to hormones and peptides, and why he brings his entire staff to medical conferences.
In this episode:-The burnout and health crisis that pushed him out of traditional practice-The financial reality of transitioning to a new practice model-From “kooky doctor” to accepted: how the field has shifted-Inside the FDA Pharmacy Compounding Advisory Committee’s peptide review-Why the vote was about compounding safety, not FDA approval-Why great clinicians rely on a handful of peptides, not twenty-Nutrition, movement, and the 80/20 approach to longevity-Why every person in a practice should understand patient care
Learn More About Dr Kris:The Resurge Clinic: https://www.theresurgeclinic.com/?utm_source=podcast&utm_medium=organicFollow Dr. Kris on Instagram:
https://www.instagram.com/drkriswusterhausen/?utm_source=podcast&utm_medium=organic
Learn more about nuBioAge: https://nubioage.com/register/?utm_source=podcast&utm_medium=organic
Learn more about the CALM conference : 
https://calm.nubioage.com/?utm_source=podcast&utm_medium=organic
Follow Leonard on Instagram:
https://www.instagram.com/leonardpastrana
This podcast is for educational purposes only and is not medical advice. Talk with your healthcare provider before making changes to your care.
Chapters 00:00 Introduction 00:46 Introducing Dr. Kris 02:10 Burned Out at the County Clinic 04:41 Finding a Different Model of Medicine 06:19 The Hard Truth About Transitioning Practices 07:43 Why Doctors Should Share Their Failures 10:23 How He Stays Ahead of the Curve 13:58 From “Kooky Doctor” to Mainstream 17:10 Better Tools, Same Basics 18:50 Why Doctors Can’t Ignore Social Media 23:50 Too Pharma for the Gym Bros 25:05 Getting the Call From the FDA 28:23 Inside the Room: BPC-157 and the Vote 30:57 Real-World Data vs. the Regulatory Process 32:22 Best Intentions on Both Sides 33:22 Longevity Without the Neurosis 38:29 Why You Don’t Need 20 Peptides 39:57 Foundations First, Then Peptides 41:44 What Patients Actually Care About 43:43 Where Traditional Medicine Lost Its Way 45:44 Health as a Smart Bet 48:11 Ask Patients What They’ll Actually Do 49:23 Why He Brings His Whole Staff to Conferences 53:33 Building Your Community 55:13 Closing Thoughts
peptides, peptide therapy, BPC-157, FDA peptides, FDA advisory committee, Pharmacy Compounding Advisory Committee, 503A compounding, compounded peptides, longevity medicine, age management medicine, hormone replacement therapy, BHRT, physician burnout, osteopathic medicine, functional medicine, real-world evidence, preventive medicine, Dr. Kris Wusterhausen, The Resurge Clinic, Leonard Pastrana, Unsee Podcast

Some moments change how you see medicine forever. Once you see them, you can't unsee them.
In this first episode Leonard Pastrana, Pharm D shares the "unseen moments" that reshaped his view of healthcare. They include a hospital committee that chose a treatment based on cost instead of what was best for the patient, and his wife's years of recurring diverticulitis flares that specialist after specialist couldn't explain. It took a physician willing to look beyond the guidelines to finally find what everyone else had missed.
 
After working in retail and hospital pharmacy, and then spending years creating education alongside leading physicians and scientists in clinical longevity medicine, he's had thousands of private conversations with doctors who practice in the gap between what's proven, what they see in patients every day, and what we're still figuring out.
 
This show brings those conversations into the open. You'll hear from physicians, scientists, and founders who treat "show me the data" as the start of the conversation, not the end.
 
In this episode:
- What an "unseen moment" is, and why it happens so often in healthcare
- Longevity medicine defined: improving health span and lifespan together
- Why earlier diagnostics are creating new uncertainty in medicine
- The personal story behind the show
 
This podcast is for educational purposes only and is not medical advice. Talk with your healthcare provider before making changes to your care.